N-Despropyl Macitentan
cas: 1103522-45-7 — see every product listed under this CAS number, including other names
N-Despropyl Macitentan (CAS 1103522-45-7) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.
| brand | Chemat Brand |
|---|---|
| catalog number | ULM128003 |
| cas | 1103522-45-7 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
ACT-132577 is a member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an antihypertensive agent, a drug metabolite, an endothelin receptor antagonist and a xenobiotic metabolite. It is an aromatic ether, an organobromine compound, a member of pyrimidines and a member of sulfamides. It is functionally related to an ethylene glycol.
Source: ChEBI
| Molecular formula | C16H14Br2N6O4S |
|---|---|
| Molecular weight | 546.2 g/mol |
| IUPAC name | 5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine |
| InChIKey | DKULOVKANLVDEA-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br |
Computed by PubChem (NCBI)