Atuveciclib, racemate, 98%
cas: 1414943-88-6 — see every product listed under this CAS number, including other names
Atuveciclib, racemate, 98% (CAS 1414943-88-6) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F840720-5MG |
| cas | 1414943-88-6 |
| size | 5mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 5mg | 638.33 Pln | |
| Fluorochem | 10mg | 810.15 Pln | |
| Fluorochem | 25mg | 1320.39 Pln | |
| Fluorochem | 50mg | 2528.29 Pln | |
| Fluorochem | 100mg | 3590.42 Pln |
properties
| purity | 98% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Atuveciclib Racemate is atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3a and GSK3b respectively.
Source: ChEBI
| Molecular formula | C18H18FN5O2S |
|---|---|
| Molecular weight | 387.4 g/mol |
| IUPAC name | 4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine |
| InChIKey | ACWKGTGIJRCOOM-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C |
Computed by PubChem (NCBI)