Products 1414943-88-6

CAS 1414943-88-6 appears in our catalog under these names: Atuveciclib Racemate, Atuveciclib (BAY-1143572), 4-(4-Fluoro-2-methoxyphenyl)-N-(3-((S-methylsulfonimidoyl)methyl)phenyl)-1,3,5-triazin-2-amine, 98%, 98%, Atuveciclib (Racemate), 98.48%, Atuveciclib, racemate, 98%. Offered by: TargetMol, Biosynth, Chemat, MedChemExpress, Fluorochem. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 5 mg.

Atuveciclib Racemate
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 704.78
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Atuveciclib (BAY-1143572)
Biosynth
  • size: 10mg, 5mg, 25mg, 50mg
  • Variants: 4
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4-(4-Fluoro-2-methoxyphenyl)-N-(3-((S-methylsulfonimidoyl)methyl)phenyl)-1,3,5-triazin-2-amine, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 270.80
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Atuveciclib (Racemate), 98.48%
MedChemExpress
  • size: 5 mg, 100 mg, 10mM/1mL, 10 mg
  • Variants: 6
from 742.30
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Atuveciclib, racemate, 98%
Fluorochem
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 638.33
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Atuveciclib Racemate, 98%
Ambeed
  • size: 250mg
  • Variants: 1
from 5554.62
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Structural formula: {0} (CAS {1})

Atuveciclib Racemate is atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3a and GSK3b respectively.

Source: ChEBI

Identity
Molecular formulaC18H18FN5O2S
Molecular weight387.4 g/mol
IUPAC name4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine
InChIKeyACWKGTGIJRCOOM-UHFFFAOYSA-N
SMILESCOC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C

Computed by PubChem (NCBI)

Synonyms: Atuveciclib Racemate, Atuveciclib (Racemate), Atuveciclib (BAY-1143572), (+)-Atuveciclib, Atuveciclib, racemate, orb1309946, orb1710321, orb1710322, Atuveciclib(BAY-1143572), ACWKGTGIJRCOOM-UHFFFAOYSA-N
Related forms of this compound
4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine C18H18FN5O2S
4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine C18H18FN5O2S
4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine C18H18FN5O2S