Products 1009817-63-3

CAS 1009817-63-3 appears in our catalog under these names: B-AP15/ 95.25% (existing batch purity), NSC 687852 (b–AP15), b-AP15, b-AP15 98%, b-AP15, 98%, 98%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 10mM (in 1ml dmso).

B-AP15/ 95.25% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 399.00
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NSC 687852 (b–AP15)
GLPBio
  • size: 10mg, 200mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 583.00
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b-AP15
Biosynth
  • size: 50mg, 10mg
  • Variants: 2
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b-AP15 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 5
from 181.25
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b-AP15, 98%, 98%
Chemat
  • size: 1mg, 25mg
  • Variants: 2
from 131.60
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b-AP15, 98.93%
MedChemExpress
  • size: 50 mg, 25 mg, 500 mg, 5 mg
  • Variants: 7
from 319.69
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(3E,5E)-1-ACRYLOYL-3,5-BIS(4-NITROBENZYLIDENE)PIPERIDIN-4-ONE, 98%
Fluorochem
  • size: 1mg
  • Variants: 1
from 216.61
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Structural formula: {0} (CAS {1})

B-AP15 is a member of the class of piperidones that is piperidin-4-one substituted by a 3-oxoprop-1-en-3-yl group at position 1 and 4-nitrobenzylidene groups at positions 3 and 5. It is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5). It has a role as an antineoplastic agent, a proteasome inhibitor, an anti-inflammatory agent and an apoptosis inducer. It is a member of acrylamides, a nitrophenol and a member of piperidones.

Source: ChEBI

Identity
Molecular formulaC22H17N3O6
Molecular weight419.4 g/mol
IUPAC name(3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one
InChIKeyGFARQYQBWJLZMW-JYFOCSDGSA-N
SMILESC=CC(=O)N1C/C(=C\C2=CC=C(C=C2)[N+](=O)[O-])/C(=O)/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C1

Computed by PubChem (NCBI)

Synonyms: b-AP15, (3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-(prop-2-enoyl)piperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one, (3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one., b-AP15(NSC687852), 1-Acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one, orb1227162, orb1307069, GFARQYQBWJLZMW-JYFOCSDGSA-N