cas: 2664214-60-0 — see every product listed under this CAS number, including other names
BI-4020, 99.30% (CAS 2664214-60-0) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 1 mg, 5 mg, 50 mg, 100 mg, 10 mg, 10mM/1mL. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-129550-25 mg |
| cas | 2664214-60-0 |
| size | 25 mg |
| availability | In stock |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 5251.62 Pln | |
| MedChemExpress | 1 mg | 1127.75 Pln | |
| MedChemExpress | 5 mg | 2520.95 Pln | |
| MedChemExpress | 50 mg | 6979.19 Pln | |
| MedChemExpress | 100 mg | 9282.61 Pln | |
| MedChemExpress | 10 mg | 3575.14 Pln | |
| MedChemExpress | 10mM/1mL | 2985.35 Pln |
| delivery time | 2-3 weeks |
|---|---|
| purity | 99.30% |
BI-4020 is a macrocycle with formula C30H38N8O2. It is a potent inhibitor of triple mutant EGFRdel19 T790M C797S variant and shows efficacy for regressing tumor xenografts in vivo. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is a member of indoles, a pyridinecarboxamide, an ether, a member of pyrazoles, a N-methylpiperazine and a macrocycle.
Source: ChEBI
| Molecular formula | C30H38N8O2 |
|---|---|
| Molecular weight | 542.7 g/mol |
| IUPAC name | (11R)-5,11,26-trimethyl-16-[(4-methylpiperazin-1-yl)methyl]-7-oxa-4,5,13,20,22,27-hexazapentacyclo[22.3.1.02,6.013,21.014,19]octacosa-1(27),2(6),3,14(19),15,17,20,24(28),25-nonaen-23-one |
| InChIKey | AIQBYZOTCIQTGW-HXUWFJFHSA-N |
| SMILES | C[C@@H]1CCCOC2=C(C=NN2C)C3=NC(=CC(=C3)C(=O)NC4=NC5=C(N4C1)C=C(C=C5)CN6CCN(CC6)C)C |
Computed by PubChem (NCBI)