Products 2664214-60-0
CAS 2664214-60-0 appears in our catalog under these names: BI-4020/ 97.21% (existing batch purity), BI–4020, BI-4020 98%, BI4020, 98%, 98%, BI-4020, 99.30%. Offered by: TargetMol, GLPBio, Ambeed, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 25 mg.
BI-4020 is a macrocycle with formula C30H38N8O2. It is a potent inhibitor of triple mutant EGFRdel19 T790M C797S variant and shows efficacy for regressing tumor xenografts in vivo. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is a member of indoles, a pyridinecarboxamide, an ether, a member of pyrazoles, a N-methylpiperazine and a macrocycle.
Source: ChEBI
| Molecular formula | C30H38N8O2 |
|---|---|
| Molecular weight | 542.7 g/mol |
| IUPAC name | (11R)-5,11,26-trimethyl-16-[(4-methylpiperazin-1-yl)methyl]-7-oxa-4,5,13,20,22,27-hexazapentacyclo[22.3.1.02,6.013,21.014,19]octacosa-1(27),2(6),3,14(19),15,17,20,24(28),25-nonaen-23-one |
| InChIKey | AIQBYZOTCIQTGW-HXUWFJFHSA-N |
| SMILES | C[C@@H]1CCCOC2=C(C=NN2C)C3=NC(=CC(=C3)C(=O)NC4=NC5=C(N4C1)C=C(C=C5)CN6CCN(CC6)C)C |
Computed by PubChem (NCBI)