BKM 120
cas: 944396-07-0 — see every product listed under this CAS number, including other names
BKM 120 (CAS 944396-07-0) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 10mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | FD64903-50mg |
| cas | 944396-07-0 |
| size | 50mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 50mg | price on request | |
| Biosynth | 10mg | price on request |
properties
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| sub-category 2 | Enzyme Modulators |
| purity | No data |
| delivery time | 1-2 weeks |
BKM120 is an aminopyridine that is 4-(trifluoromethyl)pyridin-2-amine substituted at position 5 by a 2,6-di(morpholin-4-yl)pyrimidin-4-y group. A selective PI3K inhibitor with anti-tumour properties. It has a role as an antineoplastic agent and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is an organofluorine compound, an aminopyridine, an aminopyrimidine and a member of morpholines.
Source: ChEBI
| Molecular formula | C18H21F3N6O2 |
|---|---|
| Molecular weight | 410.4 g/mol |
| IUPAC name | 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine |
| InChIKey | CWHUFRVAEUJCEF-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4 |
Computed by PubChem (NCBI)
Synonyms:
Buparlisib, buparlisibum, 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine, Buparlisib (BKM120), Buparlisib [INN], 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-Pyridinamine, 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine, 5-[2,6-Di(Morpholin-4-Yl)pyrimidin-4-Yl]-4-(Trifluoromethyl)pyridin-2-Amine, BUPARLISIB [WHO-DD], 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine