Products 944396-07-0

CAS 944396-07-0 appears in our catalog under these names: NVP-BKM 120, >95% (HPLC), Buparlisib/ 98.4% (existing batch purity), BKM120, BKM 120, Buparlisib 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 100mg, 10mg, 5mg, 25mg, 50mg, 200mg, 500mg, 10mM (in 1ml dmso).

NVP-BKM 120, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 5mg
  • Variants: 3
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Buparlisib/ 98.4% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 558.88
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BKM120
GLPBio
  • size: 10mg, 100mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 592.36
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BKM 120
Biosynth
  • size: 50mg, 10mg
  • Variants: 2
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Buparlisib 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 7
from 197.94
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5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine, 98%, 98%
Chemat
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 6
from 117.20
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Buparlisib, 99.90%
MedChemExpress
  • size: 50 mg, 500 mg, 5 mg, 100 mg
  • Variants: 7
from 463.66
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Buparlisib (Standard)
MedChemExpress
  • size: 25 mg, 10 mg, 100 mg, 50 mg
  • Variants: 5
from 811.96
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Structural formula: {0} (CAS {1})

BKM120 is an aminopyridine that is 4-(trifluoromethyl)pyridin-2-amine substituted at position 5 by a 2,6-di(morpholin-4-yl)pyrimidin-4-y group. A selective PI3K inhibitor with anti-tumour properties. It has a role as an antineoplastic agent and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is an organofluorine compound, an aminopyridine, an aminopyrimidine and a member of morpholines.

Source: ChEBI

Identity
Molecular formulaC18H21F3N6O2
Molecular weight410.4 g/mol
IUPAC name5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
InChIKeyCWHUFRVAEUJCEF-UHFFFAOYSA-N
SMILESC1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4

Computed by PubChem (NCBI)

Synonyms: Buparlisib, buparlisibum, 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine, Buparlisib (BKM120), Buparlisib [INN], 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-Pyridinamine, 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine, 5-[2,6-Di(Morpholin-4-Yl)pyrimidin-4-Yl]-4-(Trifluoromethyl)pyridin-2-Amine, BUPARLISIB [WHO-DD], 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine