BMS 195614, ≥97%, ≥97%
cas: 253310-42-8 — see every product listed under this CAS number, including other names
BMS 195614, ≥97%, ≥97% (CAS 253310-42-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 50mg, 250mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch11BJR0-10mg |
| cas | 253310-42-8 |
| size | 10mg |
| availability | 2g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 10mg | 477.20 Pln | |
| Chemat | 50mg | 1523.60 Pln | |
| Chemat | 250mg | 5171.60 Pln |
properties
| purity | ≥97% |
|---|---|
| delivery time | 3 weeks |
BMS 195614 is a carboxamide resulting from the formal condensation of the carboxy group of 5,5-dimethyl-8-(quinolin-3-yl)-5,6-dihydronaphthalene-2-carboxylic acid with the amino group of p-aminobenzoic acid. It is a neutral retinoic acid receptor (RAR) alpha-selective antagonist (Ki = 2.5 nM). It displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. It antagonizes agonist-induced coactivator (CoA) recruitment. It has a role as a retinoic acid receptor alpha antagonist. It is a secondary carboxamide, a member of benzoic acids and a member of quinolines.
Source: ChEBI
| Molecular formula | C29H24N2O3 |
|---|---|
| Molecular weight | 448.5 g/mol |
| IUPAC name | 4-[(5,5-dimethyl-8-quinolin-3-yl-6H-naphthalene-2-carbonyl)amino]benzoic acid |
| InChIKey | WGLMBRZXZDAQHP-UHFFFAOYSA-N |
| SMILES | CC1(CC=C(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C4=CC5=CC=CC=C5N=C4)C |
Computed by PubChem (NCBI)