cas: 196309-76-9 — see every product listed under this CAS number, including other names
Bay 11–7085 (CAS 196309-76-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 10mM (in 1ml dmso). Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC10345-10 |
| cas | 196309-76-9 |
| size | 10mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 657.89 Pln | |
| GLPBio | 25mg | 962.12 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 606.40 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
BAY11-7085 is a sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IB-alpha phosphorylation in cells (IC50 = 10 M) and prevents the activation of NF-B. It has a role as an autophagy inducer, a ferroptosis inducer, an antibacterial agent, an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor and an EC 2.7.11.10 (IkappaB kinase) inhibitor. It is a nitrile, a member of benzenes and a sulfone.
Source: ChEBI
| Molecular formula | C13H15NO2S |
|---|---|
| Molecular weight | 249.33 g/mol |
| IUPAC name | (E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile |
| InChIKey | VHKZGNPOHPFPER-ONNFQVAWSA-N |
| SMILES | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N |
Computed by PubChem (NCBI)