Products 845533-86-0

CAS 845533-86-0 appears in our catalog under these names: Bedaquiline fumarate/ 99.77% (existing batch purity), Bedaquiline fumarate, Bedaquiline fumarate, Bedaquiline fumarate, 98.00%, Bedaquiline fumarate, 98%, 98%. Offered by: TargetMol, GLPBio, Biosynth, Thermo Scientific (Acros), Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 10mM (in 1ml dmso).

Bedaquiline fumarate/ 99.77% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 492.36
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Bedaquiline fumarate
GLPBio
  • size: 10mg, 100mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 5
from 597.04
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Bedaquiline fumarate
Biosynth, Thermo Scientific (Acros)
  • size: 250mg, 100mg, 1g, 500mg
  • Variants: 7
from 783.98
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Bedaquiline fumarate, 98.00%
Chemat
  • size: 100mg, 25mg
  • Variants: 2
from 596.94
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Bedaquiline fumarate, 98%, 98%
Chemat
  • size: 1mg, 100mg, 250mg, 1g
  • Variants: 5
from 83.60
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Bedaquiline (fumarate), 99.99%
MedChemExpress
  • size: 10mM/1mL, 10 mg, 5 mg, 50 mg
  • Variants: 5
from 407.93
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Bedaquiline (fumarate) (Standard), 99.98%
MedChemExpress
  • size: 10 mg, 100 mg, 25 mg, 5 mg
  • Variants: 5
from 719.08
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Structural formula: {0} (CAS {1})

Bedaquiline fumarate is a fumarate salt prepared from equimolar amounts of bedaquiline and fumaric acid. It is used in combination therapy for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. It has a role as an ATP synthase inhibitor and an antitubercular agent. It contains a bedaquiline(2+).

Source: ChEBI

Identity
Molecular formulaC36H35BrN2O6
Molecular weight671.6 g/mol
IUPAC name(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol;(E)-but-2-enedioic acid
InChIKeyZLVSPMRFRHMMOY-WWCCMVHESA-N
SMILESCN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=C/C(=O)O)\C(=O)O

Computed by PubChem (NCBI)

Synonyms: Bedaquiline fumarate, Sirturo, Bedaquiline (fumarate), Bedaquiline fumarate [USAN], 845533-86-0 (fumarate), Bedaquiline Fumarate salt, Bedaquilinefumarate, Sirturo (TN), Bedaquiline fumarate?, C36H35BrN2O6