Bevirimat, >95% (HPLC)

cas: 174022-42-5 — see every product listed under this CAS number, including other names

Bevirimat, >95% (HPLC) (CAS 174022-42-5) is a chemical reagent available from Chemat. Available pack sizes: 2,5mg, 25mg. Offered by: TRC.

brandTRC
catalog numberTRC-B334700-2.5MG
cas174022-42-5
size2,5mg
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Available pack sizes

brand size price
TRC 2,5mg price on request
TRC 25mg price on request

properties

purity>95% (HPLC)
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Bevirimat is a pentacyclic triterpenoid obtained by the formal condensation of 2,2-dimethylsuccinic acid with the 3-hydroxy group of betulinic acid. It is isolated from the Chinese herb Syzygium claviflorum. The first in the class of HIV-1 maturation inhibitors to be studied in humans, bevirimat was identified as a potent HIV drug candidate and several clinical trials were conducted, but development into a new drug was plagued by numerous resistance-related problems. It has a role as a metabolite and a HIV-1 maturation inhibitor. It is a monocarboxylic acid, a pentacyclic triterpenoid and a dicarboxylic acid monoester. It is functionally related to a betulinic acid.

Source: ChEBI

Identity
Molecular formulaC36H56O6
Molecular weight584.8 g/mol
IUPAC name(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-carboxy-3-methylbutanoyl)oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
InChIKeyYJEJKUQEXFSVCJ-WRFMNRASSA-N
SMILESCC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)OC(=O)CC(C)(C)C(=O)O)C)C(=O)O

Computed by PubChem (NCBI)

Synonyms: Bevirimat, bevirimatum, 3-O-(3',3'-Dimethylsuccinyl)betulinic acid, 3-O-(3',3'-dimethylsuccinyl) betulinic acid, (3beta)-3-[(3-carboxy-3-methylbutanoyl)oxy]lup-20(29)-en-28-oic acid, (3beta)-3-((3-carboxy-3-methylbutanoyl)oxy)lup-20(29)-en-28-oic acid, dsb-2nmg, Bevirimat [INN], BVM, O-(3,3-Dimethylsuccinyl)betulinic acid

Also listed as

Bevirimat, min. 95 %, 5 mg Roth CAS 174022-42-5
Bevirimat/ 99.58% (existing batch purity) TargetMol CAS 174022-42-5
Bevirimat Biosynth CAS 174022-42-5
bevirimat, 99%, 99% Chemat CAS 174022-42-5
Bevirimat, 99.82% MedChemExpress CAS 174022-42-5
Bevirimat (Standard) MedChemExpress CAS 174022-42-5
Bevirimat, min. 95 %, 2 mg Roth CAS 174022-42-5
Bevirimat, min. 95 %, 10 mg Roth CAS 174022-42-5
Bevirimat, min. 95 %, 25 mg Roth CAS 174022-42-5