CD437
cas: 125316-60-1 — see every product listed under this CAS number, including other names
CD437 (CAS 125316-60-1) is a chemical reagent available from Chemat. Available pack sizes: 25MG, 5MG. Offered by: Sigma-Aldrich.
| brand | Sigma-Aldrich |
|---|---|
| catalog number | C5865-25MG |
| cas | 125316-60-1 |
| size | 25MG |
| availability | availability |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Sigma-Aldrich | 25MG | 2750.00 Pln | |
| Sigma-Aldrich | 5MG | 1150.00 Pln |
properties
| purity | No data |
|---|---|
| delivery time | 1-2 weeks (only if in stock, to check click on availability) |
CD437 is a naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells. It has a role as an apoptosis inducer and a retinoic acid receptor gamma agonist. It is a monocarboxylic acid, a naphthoic acid, a member of phenols and a member of adamantanes.
Source: ChEBI
| Molecular formula | C27H26O3 |
|---|---|
| Molecular weight | 398.5 g/mol |
| IUPAC name | 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid |
| InChIKey | LDGIHZJOIQSHPB-UHFFFAOYSA-N |
| SMILES | C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O |
Computed by PubChem (NCBI)
Synonyms:
AHPN, Cd 437, 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid, 6-(3-(1-adamantyl)-4-hydroxyphenyl)naphthalene-2-carboxylic acid, Ro-47-2077, O-Desmethyl Adapalene, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic Acid, 6-(3-(adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid, 6-[3-(1-adamantyl)-4-hydroxy-phenyl]naphthalene-2-carboxylic acid