CHIR-98014, 98%, 98%
cas: 252935-94-7 — see every product listed under this CAS number, including other names
CHIR-98014, 98%, 98% (CAS 252935-94-7) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 50mg, 100mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch11BF3V-25mg |
| cas | 252935-94-7 |
| size | 25mg |
| availability | 0.3g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 25mg | 477.20 Pln | |
| Chemat | 50mg | 770.00 Pln | |
| Chemat | 100mg | 1264.40 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
CHIR-98014 is a member of the class of aminopyrimidines that is pyrimidine substituted by {2-[(6-amino-5-nitropyridin-2-yl)amino]ethyl}amino, 2,4-dichlorophenyl, and 1H-imidazol-1-yl groups at positions 2, 4 and 5, respectively. It is a potent ATP-competitive inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.65 and 0.58 nM, respectively). It has a role as a Wnt signalling activator, a tau aggregation inhibitor, a hypoglycemic agent, an antineoplastic agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a dichlorobenzene, a member of imidazoles, a C-nitro compound, an aminopyrimidine, a secondary amino compound and a diaminopyridine.
Source: ChEBI
| Molecular formula | C20H17Cl2N9O2 |
|---|---|
| Molecular weight | 486.3 g/mol |
| IUPAC name | 6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine |
| InChIKey | MDZCSIDIPDZWKL-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N |
Computed by PubChem (NCBI)