CAS 1895895-38-1 appears in our catalog under these names: CHZ868, CHZ868/ 99.38% (existing batch purity), CHZ868 98%, N-(4-((2-((2,4-Difluorophenyl)amino)-1,4-dimethyl-1H-benzo[d]imidazol-5-yl)oxy)pyridin-2-yl)acetamide, 99.38% ,, 99.38% ,, CHZ868, 99.38%. Offered by: GLPBio, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: 10mg, 25mg, 2mg, 1mg, 5mg, 50mg, 100mg, 250mg.
CHZ868 is a memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl)oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity. It has a role as an antineoplastic agent and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of acetamides, a member of benzimidazoles, a member of pyridines, an aromatic amine, an aromatic ether, a difluorobenzene and a secondary amino compound.
Source: ChEBI
| Molecular formula | C22H19F2N5O2 |
|---|---|
| Molecular weight | 423.4 g/mol |
| IUPAC name | N-[4-[2-(2,4-difluoroanilino)-1,4-dimethylbenzimidazol-5-yl]oxy-2-pyridinyl]acetamide |
| InChIKey | KQQLBXFPTDVFAJ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC2=C1N=C(N2C)NC3=C(C=C(C=C3)F)F)OC4=CC(=NC=C4)NC(=O)C |
Computed by PubChem (NCBI)