Cabazitaxel

cas: 183133-96-2 — see every product listed under this CAS number, including other names

Cabazitaxel (CAS 183133-96-2) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 10mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: Chemat Brand, Mikromol, GLPBio, Biosynth.

brandChemat Brand
catalog numberULC942
cas183133-96-2
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat Brand on request price on request
Mikromol 250mg price on request
GLPBio 10mg 625.12 Pln
GLPBio 100mg 1046.37 Pln
GLPBio 25mg 845.11 Pln
GLPBio 5mg 536.19 Pln
GLPBio 10mM (in 1ml dmso) 634.48 Pln
GLPBio 50mg 751.50 Pln
Biosynth 1g price on request
Biosynth 0,5g price on request
Biosynth 2g price on request
Biosynth 10g price on request
Biosynth 5g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Cabazitaxel is a tetracyclic diterpenoid that is 10-deacetylbaccatin III having O-methyl groups attached at positions 7 and 10 as well as an O-(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl group attached at position 13. Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly. It has a role as an antineoplastic agent and a microtubule-stabilising agent. It is functionally related to a 10-deacetylbaccatin III.

Source: ChEBI

Identity
Molecular formulaC45H57NO14
Molecular weight835.9 g/mol
IUPAC name[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
InChIKeyBMQGVNUXMIRLCK-OAGWZNDDSA-N
SMILESCC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC

Computed by PubChem (NCBI)

Synonyms: CABAZITAXEL, Jevtana, Taxoid XRP6258, Xrp6258, Cabazitaxelum, Jevtana Kit, Cabazitaxel Injection, kabazitaxel, Jevtana (TN), cabazitaxel acetonate
Related forms of this compound
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2S,3R)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]oxycarbonylamino]-2-hydroxy-3-phenylpropanoyl]oxy-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis(trideuteriomethoxy)-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14

Also listed as

Cabazitaxel, 98% Combi-blocks CAS 183133-96-2
Cabazitaxel, >95% (HPLC) TRC CAS 183133-96-2
Cabazitaxel/ 98.14% (existing batch purity) TargetMol CAS 183133-96-2
Cabazitaxel, >98.0%(HPLC) TCI CAS 183133-96-2
Cabazitaxel, 98.00% Chemat CAS 183133-96-2
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-, 99%, 99% Chemat CAS 183133-96-2
Cabazitaxel (Standard) MedChemExpress CAS 183133-96-2
Cabazitaxel, 99.98% MedChemExpress CAS 183133-96-2
CABAZITAXEL, 99% Fluorochem CAS 183133-96-2