Products 183133-96-2

CAS 183133-96-2 appears in our catalog under these names: Cabazitaxel, 98%, Cabazitaxel, Cabazitaxel, >95% (HPLC), Cabazitaxel/ 98.14% (existing batch purity), Cabazitaxel, >98.0%(HPLC). Offered by: Combi-blocks, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 250mg, 1g, 100mg, on request, 500mg, 5mg, 20mg, 10mg.

Cabazitaxel, 98%
Combi-blocks, Thermo Scientific (Acros)
  • size: 250mg, 1g, 100mg, 500MG
  • Variants: 5
from 886.44
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Cabazitaxel
Chemat Brand, Mikromol, GLPBio
  • size: on request, 250mg, 10mg, 100mg
  • Variants: 13
from 536.19
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Cabazitaxel, >95% (HPLC)
TRC
  • size: 100mg, 500mg, 5mg
  • Variants: 3
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Cabazitaxel/ 98.14% (existing batch purity)
TargetMol
  • size: 20mg
  • Variants: 1
from 518.63
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Cabazitaxel, >98.0%(HPLC)
TCI
  • size: 25mg, 100mg
  • Variants: 2
from 319.95
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Cabazitaxel, 98.00%
Chemat
  • size: 100mg, 25mg
  • Variants: 2
from 339.13
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Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-, 99%, 99%
Chemat
  • size: 100mg, 250mg, 500mg, 1g
  • Variants: 5
from 179.60
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Cabazitaxel (Standard)
MedChemExpress
  • size: 10 mg, 5 mg, 50 mg, 25 mg
  • Variants: 5
from 551.89
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Cabazitaxel, 99.98%
MedChemExpress
  • size: 500 mg, 10 mg, 50 mg, 5 mg
  • Variants: 7
from 287.18
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CABAZITAXEL, 99%
Fluorochem
  • size: 100mg, 250mg, 500mg, 1g
  • Variants: 5
from 289.50
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Structural formula: {0} (CAS {1})

Cabazitaxel is a tetracyclic diterpenoid that is 10-deacetylbaccatin III having O-methyl groups attached at positions 7 and 10 as well as an O-(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl group attached at position 13. Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly. It has a role as an antineoplastic agent and a microtubule-stabilising agent. It is functionally related to a 10-deacetylbaccatin III.

Source: ChEBI

Identity
Molecular formulaC45H57NO14
Molecular weight835.9 g/mol
IUPAC name[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
InChIKeyBMQGVNUXMIRLCK-OAGWZNDDSA-N
SMILESCC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC

Computed by PubChem (NCBI)

Synonyms: CABAZITAXEL, Jevtana, Taxoid XRP6258, Xrp6258, Cabazitaxelum, Jevtana Kit, Cabazitaxel Injection, kabazitaxel, Jevtana (TN), cabazitaxel acetonate
Related forms of this compound
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2S,3R)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]oxycarbonylamino]-2-hydroxy-3-phenylpropanoyl]oxy-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis(trideuteriomethoxy)-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate C45H57NO14