Products 2417489-10-0
CAS 2417489-10-0 appears in our catalog under these names: RP–3500, Camonsertib/ 99.6% (existing batch purity), Camonsertib 99%, RP-3500, 99%, 99%, Camonsertib, 99.99%. Offered by: GLPBio, TargetMol, Ambeed, Chemat, MedChemExpress. Available pack sizes: 10mg, 1mg, 5mg, 25mg, 50mg, 100mg, 250mg, 25 mg.
Camonsertib is a pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine substituted by 1H-pyrazol-3-yl, (3-endo)-3-hydroxy-8-oxabicyclo[3.2.1]octan-3-yl, and (3R)-3-methylmorpholin-4-yl groups at positions 1, 4 and 6, respectively. It is a highly potent and selective inhibitor of ATR kinase (IC50 = 1 nM). It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of imidazoles, a tertiary alcohol, a member of morpholines, a pyrazolopyridine and an oxabicycloalkane.
Source: ChEBI
| Molecular formula | C21H26N6O3 |
|---|---|
| Molecular weight | 410.5 g/mol |
| IUPAC name | (1R,5S)-3-[6-[(3R)-3-methylmorpholin-4-yl]-1-(1H-pyrazol-5-yl)pyrazolo[5,4-b]pyridin-4-yl]-8-oxabicyclo[3.2.1]octan-3-ol |
| InChIKey | YIHHYCIYAIVQKX-YNOVCBQDSA-N |
| SMILES | C[C@@H]1COCCN1C2=NC3=C(C=NN3C4=CC=NN4)C(=C2)C5(C[C@H]6CC[C@@H](C5)O6)O |
Computed by PubChem (NCBI)