Capmatinib

cas: 1029712-80-8 — see every product listed under this CAS number, including other names

Capmatinib (CAS 1029712-80-8) is a chemical reagent available from Chemat. Available pack sizes: 0,025g, 0,05g, 0,1g, 0,5g, 0,25g. Offered by: Biosynth.

brandBiosynth
catalog numberFF40658-0,025g
cas1029712-80-8
size0,025g
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Available pack sizes

brand size price
Biosynth 0,025g price on request
Biosynth 0,05g price on request
Biosynth 0,1g price on request
Biosynth 0,5g price on request
Biosynth 0,25g price on request

properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Capmatinib is a member of the class of imidazotriazines that is imidazo[1,2-b][1,2,4]triazine substituted by 3-fluoro-4-(methylcarbamoyl)phenyl and quinolin-6-ylmethyl groups at positions 2 and 7, respectively. It is a c-Met receptor tyrosine kinase inhibitor used for the treatment of non-small cell lung cancer with MET exon 14 skipping mutation. It has a role as an antineoplastic agent, a hepatotoxic agent, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a secondary carboxamide, a member of benzamides, a member of quinolines, an imidazotriazine and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC23H17FN6O
Molecular weight412.4 g/mol
IUPAC name2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide
InChIKeyLIOLIMKSCNQPLV-UHFFFAOYSA-N
SMILESCNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F

Computed by PubChem (NCBI)

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