Products 1029712-80-8
CAS 1029712-80-8 appears in our catalog under these names: INCB28060, 95%, Capmatinib/ 99.76% (existing batch purity), INCB28060, Capmatinib, 2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, 99%, 99%. Offered by: Combi-blocks, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 250mg, 1g, 100mg, 5mg, 10mg, 25mg, 50mg, 200mg.
Capmatinib is a member of the class of imidazotriazines that is imidazo[1,2-b][1,2,4]triazine substituted by 3-fluoro-4-(methylcarbamoyl)phenyl and quinolin-6-ylmethyl groups at positions 2 and 7, respectively. It is a c-Met receptor tyrosine kinase inhibitor used for the treatment of non-small cell lung cancer with MET exon 14 skipping mutation. It has a role as an antineoplastic agent, a hepatotoxic agent, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a secondary carboxamide, a member of benzamides, a member of quinolines, an imidazotriazine and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H17FN6O |
|---|---|
| Molecular weight | 412.4 g/mol |
| IUPAC name | 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide |
| InChIKey | LIOLIMKSCNQPLV-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F |
Computed by PubChem (NCBI)