Cobimetinib (hemifumarate)

cas: 1369665-02-0 — see every product listed under this CAS number, including other names

Cobimetinib (hemifumarate) (CAS 1369665-02-0) is a chemical reagent available from Chemat. Available pack sizes: 2mg, 5mg, 50mg. Offered by: Chemat.

brandChemat
catalog numberCh12E7MP-2mg
cas1369665-02-0
size2mg
availability 0.05g
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat 2mg 328.40 Pln
Chemat 5mg 602.00 Pln
Chemat 50mg 4264.40 Pln

properties

delivery time3 weeks
Structural formula: {0} (CAS {1})

Cobimetinib fumarate is a fumarate salt prepared from cobimetinib by reaction of one molecule of fumaric acid for every two molecules of cobimetinib. An inhibitor of mitogen-activated protein kinase that is used in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is an organoammonium salt and a fumarate salt. It contains a cobimetinib(1+).

Source: ChEBI

Identity
Molecular formulaC46H46F6I2N6O8
Molecular weight1178.7 g/mol
IUPAC name(E)-but-2-enedioic acid;bis([3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone)
InChIKeyRESIMIUSNACMNW-BXRWSSRYSA-N
SMILESC1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C(=C/C(=O)O)\C(=O)O

Computed by PubChem (NCBI)

Synonyms: Cobimetinib Fumarate, Cobimetinib hemifumarate, Xl-518 hemifumarate, Cobimetinib fumarate [USAN], Cobimetinib fumarate (USAN), Cobimetinib fumarate - Bio-X, Cotellic (TN), orb1685865, COBIMETINIB FUMARATE [MI], COBIMETINIB FUMARATE [JAN]

Also listed as

Cobimetinib hemifumarate TargetMol CAS 1369665-02-0
Cobimetinib fumarate Biosynth CAS 1369665-02-0
Cobimetinib (hemifumarate), 99.68% MedChemExpress CAS 1369665-02-0