cas: 934660-93-2 — see every product listed under this CAS number, including other names
Cobimetinib (CAS 934660-93-2) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: Chemat Brand, GLPBio, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | ULC300001 |
| cas | 934660-93-2 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| GLPBio | 10mg | 919.99 Pln | |
| GLPBio | 25mg | 1617.39 Pln | |
| GLPBio | 5mg | 817.02 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 994.88 Pln | |
| GLPBio | 50mg | 2080.76 Pln | |
| Biosynth | 50mg | price on request | |
| Biosynth | 10mg | price on request |
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Cobimetinib is a member of the class of N-acylazetidines obtained by selective formal condensation of the carboxy group of 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid with the secondary amino group from the azetidine ring of 3-[(2S)-piperidin-2-yl]azetidin-3-ol. An inhibitor of mitogen-activated protein kinase that is used (as its fumarate salt) in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of piperidines, a tertiary alcohol, an aromatic amine, an organoiodine compound, a difluorobenzene, a N-acylazetidine and a secondary amino compound. It is a conjugate base of a cobimetinib(1+).
Source: ChEBI
| Molecular formula | C21H21F3IN3O2 |
|---|---|
| Molecular weight | 531.3 g/mol |
| IUPAC name | [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone |
| InChIKey | BSMCAPRUBJMWDF-KRWDZBQOSA-N |
| SMILES | C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O |
Computed by PubChem (NCBI)