Compound E (secretase inhibitor)

cas: 209986-17-4 — see every product listed under this CAS number, including other names

Compound E (secretase inhibitor) (CAS 209986-17-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 0,5mg, 2mg, 5mg, 10mg. Offered by: Biosynth.

brandBiosynth
catalog numberFD103782-1mg
cas209986-17-4
size1mg
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properties

categoryControlled Products
purityNo data
delivery time3-4 weeks
Structural formula: {0} (CAS {1})

Compound E is an L-alanine derivative that is the amide obtained by formal condensation of the carboxy group of N-[(3,5-difluorophenyl)acetyl]-L-alanine with the amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. An inhibitor of memapsin 2 (gamma-secretase). It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a 1,4-benzodiazepinone, a difluorobenzene and a L-alanine derivative.

Source: ChEBI

Identity
Molecular formulaC27H24F2N4O3
Molecular weight490.5 g/mol
IUPAC name(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]propanamide
InChIKeyJNGZXGGOCLZBFB-IVCQMTBJSA-N
SMILESC[C@@H](C(=O)N[C@@H]1C(=O)N(C2=CC=CC=C2C(=N1)C3=CC=CC=C3)C)NC(=O)CC4=CC(=CC(=C4)F)F

Computed by PubChem (NCBI)

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