Products 209986-17-4
CAS 209986-17-4 appears in our catalog under these names: Compound E (gamma-Secretase Inhibitor XXI), γ-Secretase-IN-1/ 99.56% (existing batch purity), Compound E, Compound E , Compound E (secretase inhibitor). Offered by: TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 0,5mg, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).
Compound E is an L-alanine derivative that is the amide obtained by formal condensation of the carboxy group of N-[(3,5-difluorophenyl)acetyl]-L-alanine with the amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. An inhibitor of memapsin 2 (gamma-secretase). It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a 1,4-benzodiazepinone, a difluorobenzene and a L-alanine derivative.
Source: ChEBI
| Molecular formula | C27H24F2N4O3 |
|---|---|
| Molecular weight | 490.5 g/mol |
| IUPAC name | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]propanamide |
| InChIKey | JNGZXGGOCLZBFB-IVCQMTBJSA-N |
| SMILES | C[C@@H](C(=O)N[C@@H]1C(=O)N(C2=CC=CC=C2C(=N1)C3=CC=CC=C3)C)NC(=O)CC4=CC(=CC(=C4)F)F |
Computed by PubChem (NCBI)