DADLE

cas: 63631-40-3 — see every product listed under this CAS number, including other names

DADLE (CAS 63631-40-3) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC17677-10
cas63631-40-3
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 817.02 Pln
GLPBio 100mg 2403.71 Pln
GLPBio 25mg 1224.23 Pln
GLPBio 5mg 671.93 Pln
GLPBio 10mM (in 1ml dmso) 742.14 Pln
GLPBio 50mg 1729.72 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

DADLE is a pentapeptide comprising of L-tyrosine, D-alanine, glycine, L-phenylalanine and D-leucine residues joined in sequence by peptide linkages. It is a synthetic delta-opioid agonist that induces hibernation, promotes survival of neurons and glial cells in the CNS, and exerts neuroprotection. It has a role as an autophagy inducer, a geroprotector, an antinociceptive agent, an opioid analgesic, a mu-opioid receptor agonist, a neuroprotective agent, a delta-opioid receptor agonist and a cardioprotective agent.

Source: ChEBI

Identity
Molecular formulaC29H39N5O7
Molecular weight569.6 g/mol
IUPAC name(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
InChIKeyZHUJMSMQIPIPTF-IBURTVSXSA-N
SMILESC[C@H](C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)N

Computed by PubChem (NCBI)

Synonyms: DADLE, DADL, [D-Ala2, D-Leu5]-enkephalin, Leucine enkephalin-2-alanine, Enkephalin-leu,ala(2), 2-Alanyl-leucine enkephalin, 5-Leucine-2-alanine enkephalin, (D-Ala2, D-Leu5)-Enkephalin, D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-, Leu Enkephalin 2 Ala
Related forms of this compound
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid C29H39N5O7
(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid C29H39N5O7

Also listed as

BW-180C/ 100% TargetMol CAS 63631-40-3
(D-Ala2,D-Leu5)-Enkephalin Biosynth CAS 63631-40-3
H-Tyr-D-Ala-Gly-Phe-D-Leu-OH, ≥95%, ≥95% Chemat CAS 63631-40-3
BW-180C, 99.92% MedChemExpress CAS 63631-40-3