Products 63631-40-3

CAS 63631-40-3 appears in our catalog under these names: BW-180C/ 100%, DADLE, (D-Ala2,D-Leu5)-Enkephalin, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH, ≥95%, ≥95%, BW-180C, 99.92%. Offered by: TargetMol, GLPBio, Biosynth, Chemat, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).

BW-180C/ 100%
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 445.96
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DADLE
GLPBio
  • size: 10mg, 100mg, 25mg, 5mg
  • Variants: 6
from 671.93
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(D-Ala2,D-Leu5)-Enkephalin
Biosynth
  • size: 100mg, 0,5mg, 50mg, 250mg
  • Variants: 4
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H-Tyr-D-Ala-Gly-Phe-D-Leu-OH, ≥95%, ≥95%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 208.40
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BW-180C, 99.92%
MedChemExpress
  • size: 100 mg, 10 mg, 25 mg, 5 mg
  • Variants: 6
from 454.37
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Structural formula: {0} (CAS {1})

DADLE is a pentapeptide comprising of L-tyrosine, D-alanine, glycine, L-phenylalanine and D-leucine residues joined in sequence by peptide linkages. It is a synthetic delta-opioid agonist that induces hibernation, promotes survival of neurons and glial cells in the CNS, and exerts neuroprotection. It has a role as an autophagy inducer, a geroprotector, an antinociceptive agent, an opioid analgesic, a mu-opioid receptor agonist, a neuroprotective agent, a delta-opioid receptor agonist and a cardioprotective agent.

Source: ChEBI

Identity
Molecular formulaC29H39N5O7
Molecular weight569.6 g/mol
IUPAC name(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
InChIKeyZHUJMSMQIPIPTF-IBURTVSXSA-N
SMILESC[C@H](C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)N

Computed by PubChem (NCBI)

Synonyms: DADLE, DADL, [D-Ala2, D-Leu5]-enkephalin, Leucine enkephalin-2-alanine, Enkephalin-leu,ala(2), 2-Alanyl-leucine enkephalin, 5-Leucine-2-alanine enkephalin, (D-Ala2, D-Leu5)-Enkephalin, D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-, Leu Enkephalin 2 Ala
Related forms of this compound
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid C29H39N5O7
(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid C29H39N5O7