DDR1–IN–1
cas: 1449685-96-4 — see every product listed under this CAS number, including other names
DDR1–IN–1 (CAS 1449685-96-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC17365-10 |
| cas | 1449685-96-4 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1051.05 Pln | |
| GLPBio | 100mg | 5048.20 Pln | |
| GLPBio | 5mg | 812.34 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 901.27 Pln | |
| GLPBio | 50mg | 3278.97 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
DDR1-IN-1 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzoic acid with the amino group of 5-(5-amino-2-methylphenoxy)-1,3-dihydro-2H-indol-2-one. It is a potent inhibitor of discoidin domain receptor tyrosine kinase 1 and 2 (DDR1/2) with IC50 = 105 nM and 413 nM, respectively. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a secondary carboxamide, a member of benzamides, an aromatic ether, a member of oxindoles, a N-alkylpiperazine and a member of (trifluoromethyl)benzenes.
Source: ChEBI
| Molecular formula | C30H31F3N4O3 |
|---|---|
| Molecular weight | 552.6 g/mol |
| IUPAC name | 4-[(4-ethylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(2-oxo-1,3-dihydroindol-5-yl)oxy]phenyl]-3-(trifluoromethyl)benzamide |
| InChIKey | AOZPVMOOEJAZGK-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F |
Computed by PubChem (NCBI)