Dactolisib (NVP-BEZ 235)

cas: 915019-65-7 — see every product listed under this CAS number, including other names

Dactolisib (NVP-BEZ 235) (CAS 915019-65-7) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULK031066
cas915019-65-7
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Dactolisib is an imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and a mTOR inhibitor. It is a nitrile, a member of quinolines, a ring assembly, an imidazoquinoline and a member of ureas.

Source: ChEBI

Identity
Molecular formulaC30H23N5O
Molecular weight469.5 g/mol
IUPAC name2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]propanenitrile
InChIKeyJOGKUKXHTYWRGZ-UHFFFAOYSA-N
SMILESCC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5

Computed by PubChem (NCBI)

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