Dasatinib

cas: 302962-49-8 — see every product listed under this CAS number, including other names

Dasatinib (CAS 302962-49-8) is a chemical reagent available from Chemat. Available pack sizes: on request, 10g, 5g, 25g, 50g, 100g, 100MG. Offered by: Chemat Brand, Biosynth, Supelco.

brandChemat Brand
catalog numberULD301
cas302962-49-8
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat Brand on request price on request
Biosynth 10g price on request
Biosynth 5g price on request
Biosynth 25g price on request
Biosynth 50g price on request
Biosynth 100g price on request
Supelco 100MG 1689.00 Pln

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Dasatinib (anhydrous) is an aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN). It has a role as an anticoronaviral agent, an antineoplastic agent and a tyrosine kinase inhibitor. It is a monocarboxylic acid amide, an organochlorine compound, an aminopyrimidine, a member of 1,3-thiazoles, a N-arylpiperazine, a N-(2-hydroxyethyl)piperazine, a secondary amino compound and a tertiary amino compound. It is a conjugate base of a dasatinib(1+).

Source: ChEBI

Identity
Molecular formulaC22H26ClN7O2S
Molecular weight488.0 g/mol
IUPAC nameN-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
InChIKeyZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILESCC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO

Computed by PubChem (NCBI)

Synonyms: Dasatinib, Sprycel, Dasatinib anhydrous, Dasatinib (anhydrous), dasatinibum, anh. dasatinib, anhydrous dasatinib, dasatinib (anh.), BMS Dasatinib, JLTN compound
Related forms of this compound
N-(2-chloro-6-methylphenyl)-2-[[2-methyl-6-[2,2,3,3,5,5,6,6-octadeuterio-4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide C22H26ClN7O2S
N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl(4,5,6-13C3)pyrimidin-4-yl](15N)amino]-(213C,315N)1,3-thiazole-5-carboxamide C22H26ClN7O2S
N-(2-chloro-6-methylphenyl)-2-[[2-methyl-6-[4-(1,1,2,2-tetradeuterio-2-hydroxyethyl)piperazin-1-yl]pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide C22H26ClN7O2S

Also listed as

Dasatinib, >95% (HPLC) TRC CAS 302962-49-8
Dasatinib/ 99.89% (existing batch purity) TargetMol CAS 302962-49-8
Dasatinib (BMS–354825) GLPBio CAS 302962-49-8
Dasatinib - Bio-X â„¢ Biosynth CAS 302962-49-8
Dasatinib, >95.0%(HPLC)(T) TCI CAS 302962-49-8
Dasatinib, 98.00% Chemat CAS 302962-49-8
Dasatinib (GMP) MedChemExpress CAS 302962-49-8
Dasatinib, min. 95 %, BioScience Grade, 100 mg Roth CAS 302962-49-8
Dasatinib, 5 g Roth CAS 302962-49-8
Dasatinib, 10 g Roth CAS 302962-49-8
Dasatinib, 25 g Roth CAS 302962-49-8
Dasatinib, 99.85% MedChemExpress CAS 302962-49-8
Dasatinib (GMP Like) MedChemExpress CAS 302962-49-8
Dasatinib (Standard), 99.64% MedChemExpress CAS 302962-49-8
Dasatinib, 98% Ambeed CAS 302962-49-8
N-(2-Chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide, 98% BLDpharm CAS 302962-49-8