cas: 56-94-0 — see every product listed under this CAS number, including other names
Demecarium Bromide (BC–48) (CAS 56-94-0) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC31190-10 |
| cas | 56-94-0 |
| size | 10mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 681.29 Pln | |
| GLPBio | 100mg | 1214.87 Pln | |
| GLPBio | 25mg | 840.43 Pln | |
| GLPBio | 5mg | 606.40 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 714.05 Pln | |
| GLPBio | 50mg | 1008.92 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Demecarium bromide is the methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is a bromide salt, a carbamate ester and a quaternary ammonium salt. It contains a demarcarium.
Source: ChEBI
| Molecular formula | C32H52Br2N4O4 |
|---|---|
| Molecular weight | 716.6 g/mol |
| IUPAC name | trimethyl-[3-[methyl-[10-[methyl-[3-(trimethylazaniumyl)phenoxy]carbonylamino]decyl]carbamoyl]oxyphenyl]azanium dibromide |
| InChIKey | YHKBUDZECQDYBR-UHFFFAOYSA-L |
| SMILES | CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C.[Br-].[Br-] |
Computed by PubChem (NCBI)