Demeclocycline

cas: 127-33-3 — see every product listed under this CAS number, including other names

Demeclocycline (CAS 127-33-3) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 25mg, 10mg, 50mg, 100mg. Offered by: GLPBio, Biosynth.

brandGLPBio
catalog numberGF14710-5mg
cas127-33-3
size5mg
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Available pack sizes

brand size price
GLPBio 5mg 877.87 Pln
Biosynth 25mg price on request
Biosynth 10mg price on request
Biosynth 50mg price on request
Biosynth 100mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Demeclocycline is tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. It has a role as a geroprotector, an aquaretic and an antibacterial drug.

Source: ChEBI

Identity
Molecular formulaC21H21ClN2O8
Molecular weight464.9 g/mol
IUPAC name(4S,4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
InChIKeyGUXHBMASAHGULD-SEYHBJAFSA-N
SMILESCN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O

Computed by PubChem (NCBI)

Synonyms: demeclocycline, Demethylchlortetracycline, DMCT, Ledermycin, 6-Demethyl-7-chlorotetracycline, Demethylchlortetracyclin, Demeclociclina, 7-Chloro-6-demethyltetracycline, Demeclocyclinum, Clortetrin
Related forms of this compound
(4S,4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide C21H21ClN2O8
(4R,4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide C21H21ClN2O8

Also listed as

Chlortetracycline EP Impurity B,Demeclocycline Chemat Brand CAS 127-33-3
Demeclocycline/ 97.46% (existing batch purity) TargetMol CAS 127-33-3
(4S,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide, 98%, 98% Chemat CAS 127-33-3
Demeclocycline, 98.0% MedChemExpress CAS 127-33-3
Demeclocycline (Standard) MedChemExpress CAS 127-33-3
(4S,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide, 98% Chemat CAS 127-33-3