Dirithromycin

cas: 62013-04-1 — see every product listed under this CAS number, including other names

Dirithromycin (CAS 62013-04-1) is a chemical reagent available from Chemat. Available pack sizes: on request, 1g, 500mg, 25mg, 1EA. Offered by: Chemat Brand, GLPBio, Chemat, Sigma-Aldrich.

brandChemat Brand
catalog numberULD106001
cas62013-04-1
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 1g 573.64 Pln
GLPBio 500mg 517.47 Pln
Chemat 1g 1010.90 Pln
Chemat 25mg 212.94 Pln
Sigma-Aldrich 1EA 665.70 Pln

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Dirithromycin is the hemi-aminal resulting from the condensation of the erythromycin derivative (9S)-erythromycyclamine with 2-(2-methoxyethoxy)acetaldehyde. As the oxazine ring containing the hemi-aminal group is unstable under both acidic and alkaline conditions, dirithromycin functions as a more lipid-soluble prodrug for (9S)-erythromycyclamine. Administered as enteric coated tablets to protect it from acid catalysed hydrolysis in the stomach, it is used to treat respiratory tract, skin, and soft tissue infections caused by susceptible organisms. It has a role as a prodrug.

Source: ChEBI

Identity
Molecular formulaC42H78N2O14
Molecular weight835.1 g/mol
IUPAC name(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-2,10-dihydroxy-7-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-15-(2-methoxyethoxymethyl)-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one
InChIKeyWLOHNSSYAXHWNR-DWIOZXRMSA-N
SMILESCC[C@@H]1[C@@]([C@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O

Computed by PubChem (NCBI)

Synonyms: Dirithromycin, Dirithromycine, Dynabac, Diritromicina, Dirithromycinum, Dirithromycin-13C-d3, Prestwick3_000557, DIRITHROMYCIN [USAN], Dirithromycine [French], Dirithromycinum [Latin]
Isomers (same molecular formula)
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one C42H78N2O14

Also listed as

Dirithromycin, 98% Combi-blocks CAS 62013-04-1
Dirithromycin, >95% (HPLC) TRC CAS 62013-04-1
Dirithromycin/ 99.59% (existing batch purity) TargetMol CAS 62013-04-1
Dirithromycin, >98.0%(HPLC)(N) TCI CAS 62013-04-1
Dirithromycin 98% Ambeed CAS 62013-04-1
Dirithromycin, 98%, 98% Chemat CAS 62013-04-1
Dirithromycin, 98.0% MedChemExpress CAS 62013-04-1
Dirithromycin (Standard) MedChemExpress CAS 62013-04-1
Dirithromycin-13C-d3 Chemat Brand CAS 62013-04-1 (non-labelled)