Products 62013-04-1

CAS 62013-04-1 appears in our catalog under these names: Dirithromycin, 98%, Dirithromycin, Dirithromycin, >95% (HPLC), Dirithromycin/ 99.59% (existing batch purity), Dirithromycin, >98.0%(HPLC)(N). Offered by: Combi-blocks, Chemat Brand, TRC, GLPBio, TargetMol. Available pack sizes: 5g, 1g, on request, 100mg, 10g, 5mg, 500mg, 200mg.

Dirithromycin, 98%
Combi-blocks
  • size: 5g, 1g
  • Variants: 2
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Dirithromycin
Chemat Brand, GLPBio, Chemat
  • size: on request, 1g, 500mg, 25mg
  • Variants: 6
from 212.94
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Dirithromycin, >95% (HPLC)
TRC
  • size: 100mg, 10g, 5mg
  • Variants: 3
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Dirithromycin/ 99.59% (existing batch purity)
TargetMol
  • size: 1g, 200mg, 500mg
  • Variants: 3
from 405.71
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Dirithromycin, >98.0%(HPLC)(N)
TCI
  • size: 1g
  • Variants: 1
from 555.98
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Dirithromycin 98%
Ambeed
  • size: 250mg, 5g, 25g
  • Variants: 3
from 120.06
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Dirithromycin, 98%, 98%
Chemat
  • size: 250mg, 1g, 5g, 25g
  • Variants: 4
from 78.80
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Dirithromycin, 98.0%
MedChemExpress
  • size: 1 g, 100 mg, 500 mg, 10mM/1mL
  • Variants: 4
from 287.18
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Dirithromycin (Standard)
MedChemExpress
  • size: 25 mg, 100 mg, 50 mg, 10 mg
  • Variants: 4
from 268.61
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Dirithromycin-13C-d3
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Dirithromycin is the hemi-aminal resulting from the condensation of the erythromycin derivative (9S)-erythromycyclamine with 2-(2-methoxyethoxy)acetaldehyde. As the oxazine ring containing the hemi-aminal group is unstable under both acidic and alkaline conditions, dirithromycin functions as a more lipid-soluble prodrug for (9S)-erythromycyclamine. Administered as enteric coated tablets to protect it from acid catalysed hydrolysis in the stomach, it is used to treat respiratory tract, skin, and soft tissue infections caused by susceptible organisms. It has a role as a prodrug.

Source: ChEBI

Identity
Molecular formulaC42H78N2O14
Molecular weight835.1 g/mol
IUPAC name(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-2,10-dihydroxy-7-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-15-(2-methoxyethoxymethyl)-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one
InChIKeyWLOHNSSYAXHWNR-DWIOZXRMSA-N
SMILESCC[C@@H]1[C@@]([C@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O

Computed by PubChem (NCBI)

Synonyms: Dirithromycin, Dirithromycine, Dynabac, Diritromicina, Dirithromycinum, Dirithromycin-13C-d3, Prestwick3_000557, DIRITHROMYCIN [USAN], Dirithromycine [French], Dirithromycinum [Latin]
Isomers (same molecular formula)
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one C42H78N2O14