Products 57808-66-9

CAS 57808-66-9 appears in our catalog under these names: Domperidone, 98%, Domperidone, Domperidone 1.0 mg/ml in Methanol, Domperidone, >95% (HPLC), Domperidone/ 99.73% (existing batch purity). Offered by: Combi-blocks, Chemat Brand, Hubei YoungXin, Mikromol, LoGiCal. Available pack sizes: 100g, 1g, 5g, 25g, on request, 10mg, 25mg, 50mg.

Structural formula: {0} (CAS {1})

Domperidone is 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations. It has a role as a dopaminergic antagonist and an antiemetic. It is a member of benzimidazoles and a heteroarylpiperidine.

Source: ChEBI

Identity
Molecular formulaC22H24ClN5O2
Molecular weight425.9 g/mol
IUPAC name6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
InChIKeyFGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILESC1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

Computed by PubChem (NCBI)