Eribulin Mesylate

cas: 441045-17-6 — see every product listed under this CAS number, including other names

Eribulin Mesylate (CAS 441045-17-6) is a chemical reagent available from Chemat. Available pack sizes: on request, 500μg, 1mg, 5mg, 2mg, 10mg, 25mg. Offered by: Chemat Brand, GLPBio, Biosynth.

brandChemat Brand
catalog numberULE110001
cas441045-17-6
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 500μg 2941.97 Pln
GLPBio 1mg 4458.45 Pln
Biosynth 5mg price on request
Biosynth 2mg price on request
Biosynth 10mg price on request
Biosynth 25mg price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Eribulin mesylate is a methanesulfonate salt obtained by reaction of eribulin with one equivalent of methanesulfonic acid. A fully synthetic macrocyclic ketone analogue of marine sponge natural products. Inhibits growth phase of microtubules via tubulin-based antimitotic mechanism, which leads to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It contains an eribulin(1+).

Source: ChEBI

Identity
Molecular formulaC41H63NO14S
Molecular weight826.0 g/mol
IUPAC name(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one;methanesulfonic acid
InChIKeyQAMYWGZHLCQOOJ-WRNBYXCMSA-N
SMILESC[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O.CS(=O)(=O)O

Computed by PubChem (NCBI)

Synonyms: Eribulin mesylate, Halaven, Eribulin mesilate, Eribulin (as mesylate), Eribulin monomethanesulfonate, B1939 mesylate, Halichondrin B Analog, Eribulin (mesylate), Eribulin mesylate [USAN], Eribulin mesylate (USAN)

Also listed as

Eribulin mesylate/ 97.02% (existing batch purity) TargetMol CAS 441045-17-6
Eribulin mesylate GLPBio CAS 441045-17-6
Eribulin Mesylate 98% Ambeed CAS 441045-17-6
Eribulin mesylate, 98%, 98% Chemat CAS 441045-17-6
Eribulin (mesylate), 99.91% MedChemExpress CAS 441045-17-6
Eribulin (mesylate) (purity>99%, single impurity ≤ 0.15%) MedChemExpress CAS 441045-17-6
Eribulin mesylate, 98% Fluorochem CAS 441045-17-6