Products 441045-17-6

CAS 441045-17-6 appears in our catalog under these names: Eribulin Mesylate, Eribulin mesylate/ 97.02% (existing batch purity), Eribulin mesylate, Eribulin Mesylate 98%, Eribulin mesylate, 98%, 98%. Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: on request, 1mg, 5mg, 10mg, 25mg, 50mg, 500μg, 2mg.

Eribulin Mesylate
Chemat Brand, Biosynth
  • size: on request, 5mg, 2mg, 10mg
  • Variants: 5
View product
Eribulin mesylate/ 97.02% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 5
from 2909.47
View product
Eribulin mesylate
GLPBio
  • size: 500μg, 1mg
  • Variants: 2
from 2941.97
View product
Eribulin Mesylate 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 492.75
View product
Eribulin mesylate, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 4
from 314.00
View product
Eribulin (mesylate), 99.91%
MedChemExpress
  • size: 100 mg, 500 μg, 25 mg, 5 mg
  • Variants: 7
from 695.86
View product
Eribulin (mesylate) (purity>99%, single impurity ≤ 0.15%)
MedChemExpress
  • size: 25 mg, 500 μg, 50 mg, 1 mg
  • Variants: 7
from 2376.98
View product
Eribulin mesylate, 98%
Fluorochem
  • size: 1mg, 5mg, 10mg
  • Variants: 3
from 575.86
View product
Structural formula: {0} (CAS {1})

Eribulin mesylate is a methanesulfonate salt obtained by reaction of eribulin with one equivalent of methanesulfonic acid. A fully synthetic macrocyclic ketone analogue of marine sponge natural products. Inhibits growth phase of microtubules via tubulin-based antimitotic mechanism, which leads to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It contains an eribulin(1+).

Source: ChEBI

Identity
Molecular formulaC41H63NO14S
Molecular weight826.0 g/mol
IUPAC name(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one;methanesulfonic acid
InChIKeyQAMYWGZHLCQOOJ-WRNBYXCMSA-N
SMILESC[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O.CS(=O)(=O)O

Computed by PubChem (NCBI)

Synonyms: Eribulin mesylate, Halaven, Eribulin mesilate, Eribulin (as mesylate), Eribulin monomethanesulfonate, B1939 mesylate, Halichondrin B Analog, Eribulin (mesylate), Eribulin mesylate [USAN], Eribulin mesylate (USAN)