Eribulin

cas: 253128-41-5 — see every product listed under this CAS number, including other names

Eribulin (CAS 253128-41-5) is a chemical reagent available from Chemat. Available pack sizes: 500μg, on request, 1mg. Offered by: GLPBio, Chemat Brand.

brandGLPBio
catalog numberGC14354-.5
cas253128-41-5
size500μg
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Available pack sizes

brand size price
GLPBio 500μg 1280.39 Pln
Chemat Brand on request price on request
GLPBio 1mg 1509.74 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Eribulin is a fully synthetic macrocyclic ketone analogue of marine sponge natural products. Inhibits growth phase of microtubules via tubulin-based antimitotic mechanism, which leads to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is a polycyclic ether, a cyclic ketone, a polyether, a primary amino compound, a macrocycle and a cyclic ketal. It is a conjugate base of an eribulin(1+).

Source: ChEBI

Identity
Molecular formulaC40H59NO11
Molecular weight729.9 g/mol
IUPAC name(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one
InChIKeyUFNVPOGXISZXJD-JBQZKEIOSA-N
SMILESC[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O

Computed by PubChem (NCBI)

Synonyms: Eribulin, eribuline, Eribulina, E-7389 free base, eribulinum, Eribulin [INN], Eribulin free, ERIBULIN [MI], ERIBULIN [VANDF], ERIBULIN [MART.]
Isomers (same molecular formula)
(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2R)-2-amino-3-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one C40H59NO11

Also listed as

Eribulin/ 99.96% (existing batch purity) TargetMol CAS 253128-41-5
Eribulin 99% Ambeed CAS 253128-41-5
Eribulin, 99%, 99% Chemat CAS 253128-41-5
Eribulin, 99.92% MedChemExpress CAS 253128-41-5