Products 159351-69-6

CAS 159351-69-6 appears in our catalog under these names: Everolimus, 95%, Everolimus, Everolimus/ 99.52% (existing batch purity), Everolimus (RAD001), Everolimus . Offered by: Combi-blocks, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 1g, 250mg, 100mg, on request, 10mg, 50mg, 5mg, 25mg.

Everolimus, 95%
Combi-blocks
  • size: 1g, 250mg, 100mg
  • Variants: 3
View product
Everolimus
Chemat Brand, TRC, Thermo Scientific (Alfa Aesar)
  • size: on request, 10mg, 50mg, 5mg
  • Variants: 14
from 887.07
View product
Everolimus/ 99.52% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 432.54
View product
Everolimus (RAD001)
GLPBio
  • size: 10mg, 100mg, 25mg, 10mM (in 1ml dmso)
  • Variants: 4
from 639.16
View product
Everolimus, 96.00%
Chemat
  • size: 1mg, 1ml, 25mg, 5mg
  • Variants: 4
from 459.86
View product
Everolimus 98%
Ambeed
  • size: 50mg, 100mg, 250mg, 1g
  • Variants: 5
from 426.00
View product
Everolimus, min. 90 %, 50 mg
Roth
  • size: 50mg
  • Variants: 1
from 986.40
View product
Everolimus, min. 90 %, 100 mg
Roth
  • size: 100mg
  • Variants: 1
from 1297.90
View product
Everolimus, min. 90 %, 250 mg
Roth
  • size: 250mg
  • Variants: 1
from 2760.97
View product
Everolimus, 99.85%
MedChemExpress
  • size: 5 mg, 100 mg, 1 g, 200 mg
  • Variants: 9
from 361.49
View product
Everolimus (Standard), 99.27%
MedChemExpress
  • size: 25 mg, 5 mg, 10 mg, 100 mg
  • Variants: 5
from 598.33
View product
Structural formula: {0} (CAS {1})

Everolimus is a macrocyclic lactone that is rapamycin in which the hydroxy group attached to the cyclohexyl moiety has been converted into the corresponding 2-hydroxyethyl ether. It is an immunosuppressant and antineoplastic agent. It has a role as an anticoronaviral agent, a geroprotector, an antineoplastic agent, an immunosuppressive agent and a mTOR inhibitor. It is a macrolide lactam, a primary alcohol, an ether, a secondary alcohol, a cyclic ketone and a cyclic acetal. It is functionally related to a member of sirolimus.

Source: ChEBI

Identity
Molecular formulaC53H83NO14
Molecular weight958.2 g/mol
IUPAC name(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
InChIKeyHKVAMNSJSFKALM-GKUWKFKPSA-N
SMILESC[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC

Computed by PubChem (NCBI)

Synonyms: Everolimus, Afinitor, Certican, Zortress, SDZ-RAD, 42-O-(2-Hydroxyethyl)rapamycin, Votubia, SDZ RAD, 40-O-(2-hydroxyethyl)-rapamycin, Rapamycin, 42-O-(2-hydroxyethyl)-
Related forms of this compound
(1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R,4R)-3-methoxy-4-(1,1,2,2-tetradeuterio-2-hydroxyethoxy)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone C53H83NO14
Isomers (same molecular formula)
(8S,11S,14R,15E,17R,18R,20R,22S,23E,25E,27E,29S,31S,34R)-1,17-dihydroxy-11-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-18,29-dimethoxy-14,16,20,22,28,34-hexamethyl-10,36-dioxa-3-azatricyclo[29.4.1.03,8]hexatriaconta-15,23,25,27-tetraene-2,9,13,19,35-pentone C53H83NO14