CAS 1083162-61-1 appears in our catalog under these names: FIN56/ 97.86% (existing batch purity), FIN56, FIN56 98+%, FIN56, 98+%, 98+%, FIN56, 99.27%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 10mM (in 1ml dmso).
FIN56 is a fluorene that is N-9H-fluoren-9-ylidenehydroxylamine substituted by N-cyclohexylsulfonyl groups at positions 2 and 7. It induces ferroptosis via degradation of GPX4 and also binds and activates squalene synthase. It has a role as a ferroptosis inducer and an EC 1.11.1.9 (glutathione peroxidase) inhibitor. It is a member of fluorenes, a ketoxime and a sulfonamide. It is functionally related to a 9-hydroxyiminofluorene-2,7-disulfonamide.
Source: ChEBI
| Molecular formula | C25H31N3O5S2 |
|---|---|
| Molecular weight | 517.7 g/mol |
| IUPAC name | 2-N,7-N-dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide |
| InChIKey | JLCFMMIWBSZOIS-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3=NO)C=C(C=C4)S(=O)(=O)NC5CCCCC5 |
Computed by PubChem (NCBI)