Products 1434048-34-6

CAS 1434048-34-6 appears in our catalog under these names: Fenebrutinib/ 98.84% (existing batch purity), GDC–0853, Fenebrutinib (GDC-0853), Fenebrutinib 98+%, 2-[1,6-Dihydro-3'-(hydroxymethyl)-1-methyl-5-[[5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl]amino]-6-oxo[3,4'-bipyridin]-2'-yl]-3,4,7,8-tetrahydro-7,7-dimethyl-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, 98+%, 98+%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg.

Fenebrutinib/ 98.84% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 6
from 425.84
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GDC–0853
GLPBio
  • size: 10mg, 2mg, 25mg, 5mg
  • Variants: 5
from 667.25
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Fenebrutinib (GDC-0853)
Biosynth
  • size: 50mg, 25mg, 100mg
  • Variants: 3
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Fenebrutinib 98+%
Ambeed
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 281.38
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2-[1,6-Dihydro-3'-(hydroxymethyl)-1-methyl-5-[[5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl]amino]-6-oxo[3,4'-bipyridin]-2'-yl]-3,4,7,8-tetrahydro-7,7-dimethyl-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, 98+%, 98+%
Chemat
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 179.60
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Fenebrutinib, 99.89%
MedChemExpress
  • size: 5 mg, 25 mg, 10 mg, 100 mg
  • Variants: 7
from 435.79
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(S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, 98+%
Fluorochem
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 5
from 320.74
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Structural formula: {0} (CAS {1})

Fenebrutinib is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, fenebrutinib inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.

Source: ChEBI

Identity
Molecular formulaC37H44N8O4
Molecular weight664.8 g/mol
IUPAC name10-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-pyridinyl]-4,4-dimethyl-1,10-diazatricyclo[6.4.0.02,6]dodeca-2(6),7-dien-9-one
InChIKeyWNEODWDFDXWOLU-QHCPKHFHSA-N
SMILESC[C@H]1CN(CCN1C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=NC=C4)N5CCN6C7=C(CC(C7)(C)C)C=C6C5=O)CO)C8COC8

Computed by PubChem (NCBI)

Synonyms: Fenebrutinib, fenebrutinibum, Bruton Tyrosine Kinase Inhibitor GDC-0853, Fenebrutinib [INN], Fenebrutinib [USAN], Fenebrutinib (GDC-0853), Example 130 [US20140194408], s8421, Fenebrutinib (USAN/INN), Fenebrutinib [USAN:INN]