Fenfluramine

cas: 458-24-2 — see every product listed under this CAS number, including other names

Fenfluramine (CAS 458-24-2) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULF108015
cas458-24-2
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Fenfluramine is a secondary amino compound that is 1-phenyl-propan-2-amine in which one of the meta-hydrogens is substituted by trifluoromethyl, and one of the hydrogens attached to the nitrogen is substituted by an ethyl group. It binds to the serotonin reuptake pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding behavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine was used as the hydrochloride for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertension. It has a role as a serotonergic agonist, an appetite depressant and a serotonin uptake inhibitor. It is a secondary amino compound and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC12H16F3N
Molecular weight231.26 g/mol
IUPAC nameN-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
InChIKeyDBGIVFWFUFKIQN-UHFFFAOYSA-N
SMILESCCNC(C)CC1=CC(=CC=C1)C(F)(F)F

Computed by PubChem (NCBI)

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