Products 1629229-37-3

CAS 1629229-37-3 appears in our catalog under these names: Fezolinetant/ 99.7% (existing batch purity), Fezolinetant (ESN–364), Fezolinetant, Fezolinetant 98%, [(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone, 98%, 98%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso), 250mg.

Fezolinetant/ 99.7% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 658.38
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Fezolinetant (ESN–364)
GLPBio
  • size: 1mg, 10mg, 10mM (in 1ml dmso), 5mg
  • Variants: 4
from 919.99
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Fezolinetant
Biosynth
  • size: 10mg, 5mg, 25mg, 50mg
  • Variants: 5
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Fezolinetant 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 381.50
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[(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone, 98%, 98%
Chemat
  • size: 250mg, 5mg, 10mg, 25mg
  • Variants: 6
from 405.20
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Fezolinetant, 99.19%
MedChemExpress
  • size: 50 mg, 10mM/1mL, 1 mg, 25 mg
  • Variants: 7
from 551.89
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FEZOLINETANT, 98%
Fluorochem
  • size: 5mg, 10mg, 25mg
  • Variants: 3
from 747.67
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Structural formula: {0} (CAS {1})

Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a tertiary carboxamide, a member of benzamides, a member of thiadiazoles, a triazolopyrazine and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC16H15FN6OS
Molecular weight358.4 g/mol
IUPAC name(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
InChIKeyPPSNFPASKFYPMN-SECBINFHSA-N
SMILESC[C@@H]1C2=NN=C(N2CCN1C(=O)C3=CC=C(C=C3)F)C4=NC(=NS4)C

Computed by PubChem (NCBI)

Synonyms: Fezolinetant, fezolinetantum, VEOZAH, Fezolinetant [USAN], Veoza, Vezoa, Fezolinetant?, Fezolinetant [MI], Fezolinetant Intermediate, FEZOLINETANT [INN]