Products 849217-64-7

CAS 849217-64-7 appears in our catalog under these names: Foretinib, 95%, Foretinib, Foretinib/ 99.7% (existing batch purity), Foretinib (GSK1363089), Foretinib 98%. Offered by: Combi-blocks, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 100mg, 250mg, 1g, on request, 25mg, 50mg, 2mg, 5mg.

Foretinib, 95%
Combi-blocks
  • size: 100mg, 250mg, 1g
  • Variants: 3
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Foretinib
Chemat Brand, TRC, Chemat
  • size: on request, 100mg, 25mg, 50mg
  • Variants: 12
from 1264.14
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Foretinib/ 99.7% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 7
from 405.71
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Foretinib (GSK1363089)
GLPBio
  • size: 10mg, 100mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 620.44
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Foretinib 98%
Ambeed
  • size: 1mg, 5mg, 50mg, 100mg
  • Variants: 6
from 142.31
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N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide, 98%, 98%
Chemat
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 107.60
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Foretinib, 99.59%
MedChemExpress
  • size: 100 mg, 10 mg, 25 mg, 5 mg
  • Variants: 6
from 533.32
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Foretinib (Standard)
MedChemExpress
  • size: 100 mg, 50 mg, 10 mg, 25 mg
  • Variants: 5
from 867.68
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Structural formula: {0} (CAS {1})

Foretinib is a quinoline substituted by 2-fluoro-4-[({1-[(4-fluorophenyl)carbamoyl]cyclopropyl}carbonyl)amino]phenoxy, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 4, 6 and 7, respectively. It is a multi-kinase inhibitor. It has a role as an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether, a dicarboxylic acid diamide, a member of morpholines, a member of cyclopropanes and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC34H34F2N4O6
Molecular weight632.7 g/mol
IUPAC name1-N'-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
InChIKeyCXQHYVUVSFXTMY-UHFFFAOYSA-N
SMILESCOC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

Computed by PubChem (NCBI)

Synonyms: Foretinib, foretinibum, MET/VEGFR-2 inhibitor GSK1363089, Multitargeted Tyrosine Kinase Inhibitor GSK1363089, Foretinib (GSK1363089), Foretinib [USAN:INN], Foretinib(XL880), xl-880, Foretinib, Foretinib(XL880)?, FORETINIB [INN]