GS–7340

cas: 379270-37-8 — see every product listed under this CAS number, including other names

GS–7340 (CAS 379270-37-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC12679-10
cas379270-37-8
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 779.58 Pln
GLPBio 100mg 2001.19 Pln
GLPBio 5mg 662.57 Pln
GLPBio 10mM (in 1ml dmso) 779.58 Pln
GLPBio 50mg 1603.35 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Tenofovir alafenamide is an L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It is a member of 6-aminopurines, an ether, a phosphoramidate ester, an isopropyl ester and a L-alanine derivative. It is functionally related to an adenine. It is a conjugate base of a tenofovir alafenamide(1+).

Source: ChEBI

Identity
Molecular formulaC21H29N6O5P
Molecular weight476.5 g/mol
IUPAC namepropan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
InChIKeyLDEKQSIMHVQZJK-CAQYMETFSA-N
SMILESC[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3

Computed by PubChem (NCBI)

Synonyms: TENOFOVIR ALAFENAMIDE, TFV Alafenamide, Vemlidy, TENOFOVIR ALAFENAMIDE [MI], Tenofovir Alafenamide-d6?, Tenofovir Alafenamide [USAN], Tenofovir Alafenamide [USAN:INN], Tenofovir alafenamida, orb1225153, orb1305529
Related forms of this compound
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate C21H29N6O5P
propan-2-yl (2R)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate C21H29N6O5P
propan-2-yl (2R)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate C21H29N6O5P
propan-2-yl (2R)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate C21H29N6O5P

Also listed as

Tenofovir Alafenamide Chemat Brand CAS 379270-37-8
Tenofovir Alafenamide (100mg/mL in Methanol) TRC CAS 379270-37-8
Tenofovir Alafenamide, >95% (HPLC) TRC CAS 379270-37-8
Tenofovir alafenamide/ 99% TargetMol CAS 379270-37-8
GS7340 GLPBio CAS 379270-37-8
Tenofovir alafenamide (free base) Biosynth CAS 379270-37-8
GS-7340, >95.0%(HPLC)(T) TCI CAS 379270-37-8
Tenofovir alafenamide 98% Ambeed CAS 379270-37-8
Tenofovir alafenamide, 99.93% MedChemExpress CAS 379270-37-8