Tenofovir alafenamide, 99.93%

cas: 379270-37-8 — see every product listed under this CAS number, including other names

Tenofovir alafenamide, 99.93% (CAS 379270-37-8) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 10mM/1mL, 50 mg, 100 mg, 25 mg, 10 mg. Offered by: MedChemExpress.

brandMedChemExpress
catalog numberHY-15232-5 mg
cas379270-37-8
size5 mg
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Available pack sizes

brand size price
MedChemExpress 5 mg 384.71 Pln
MedChemExpress 10mM/1mL 412.57 Pln
MedChemExpress 50 mg 858.40 Pln
MedChemExpress 100 mg 1123.10 Pln
MedChemExpress 25 mg 621.55 Pln
MedChemExpress 10 mg 491.52 Pln

properties

delivery time over 3 weeks
purity99.93%
Structural formula: {0} (CAS {1})

Tenofovir alafenamide is an L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It is a member of 6-aminopurines, an ether, a phosphoramidate ester, an isopropyl ester and a L-alanine derivative. It is functionally related to an adenine. It is a conjugate base of a tenofovir alafenamide(1+).

Source: ChEBI

Identity
Molecular formulaC21H29N6O5P
Molecular weight476.5 g/mol
IUPAC namepropan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
InChIKeyLDEKQSIMHVQZJK-CAQYMETFSA-N
SMILESC[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3

Computed by PubChem (NCBI)

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