GSK343 99% (HPLC)

cas: 1346704-33-3 — see every product listed under this CAS number, including other names

GSK343 99% (HPLC) (CAS 1346704-33-3) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Ambeed.

brandAmbeed
catalog numberA135977-1mg
cas1346704-33-3
size1mg
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Available pack sizes

brand size price
Ambeed 1mg 192.38 Pln
Ambeed 5mg 298.06 Pln
Ambeed 10mg 431.56 Pln
Ambeed 25mg 720.81 Pln
Ambeed 50mg 1332.69 Pln
Ambeed 100mg 2278.31 Pln

properties

purity99% (HPLC)
delivery time 1-2 weeks
ambeed catalog no.A135977
Structural formula: {0} (CAS {1})

GSK343 is a member of the class of indazoles that is 1-isopropyl-1H-indazole-4-carboxamide in which the nitrogen of the carboxamide group is substituted by a (6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl group and in which the indazole ring is substituted at position 6 by a 2-(4-methylpiperazin-1-yl)pyridin-4-yl group. A highly potent and selective EZH2 inhibitor (IC50 = 4 nM). It has a role as an EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a pyridone, an aminopyridine, a member of indazoles, a N-alkylpiperazine and a N-arylpiperazine.

Source: ChEBI

Identity
Molecular formulaC31H39N7O2
Molecular weight541.7 g/mol
IUPAC nameN-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-1-propan-2-ylindazole-4-carboxamide
InChIKeyULNXAWLQFZMIHX-UHFFFAOYSA-N
SMILESCCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C

Computed by PubChem (NCBI)

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