cas: 1346704-33-3 — see every product listed under this CAS number, including other names
GSK343 99% (HPLC) (CAS 1346704-33-3) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A135977-1mg |
| cas | 1346704-33-3 |
| size | 1mg |
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| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 192.38 Pln | |
| Ambeed | 5mg | 298.06 Pln | |
| Ambeed | 10mg | 431.56 Pln | |
| Ambeed | 25mg | 720.81 Pln | |
| Ambeed | 50mg | 1332.69 Pln | |
| Ambeed | 100mg | 2278.31 Pln |
| purity | 99% (HPLC) |
|---|---|
| delivery time | 1-2 weeks |
| ambeed catalog no. | A135977 |
GSK343 is a member of the class of indazoles that is 1-isopropyl-1H-indazole-4-carboxamide in which the nitrogen of the carboxamide group is substituted by a (6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl group and in which the indazole ring is substituted at position 6 by a 2-(4-methylpiperazin-1-yl)pyridin-4-yl group. A highly potent and selective EZH2 inhibitor (IC50 = 4 nM). It has a role as an EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a pyridone, an aminopyridine, a member of indazoles, a N-alkylpiperazine and a N-arylpiperazine.
Source: ChEBI
| Molecular formula | C31H39N7O2 |
|---|---|
| Molecular weight | 541.7 g/mol |
| IUPAC name | N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-1-propan-2-ylindazole-4-carboxamide |
| InChIKey | ULNXAWLQFZMIHX-UHFFFAOYSA-N |
| SMILES | CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C |
Computed by PubChem (NCBI)