GSK461364, 99.82%
cas: 929095-18-1 — see every product listed under this CAS number, including other names
GSK461364, 99.82% (CAS 929095-18-1) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 100 mg, 5 mg, 10 mg, 1 mg, 200 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-50877-10mM/1mL |
| cas | 929095-18-1 |
| size | 10mM/1mL |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 621.55 Pln | |
| MedChemExpress | 100 mg | 3918.79 Pln | |
| MedChemExpress | 5 mg | 542.60 Pln | |
| MedChemExpress | 10 mg | 909.48 Pln | |
| MedChemExpress | 1 mg | 315.05 Pln | |
| MedChemExpress | 200 mg | 5818.19 Pln | |
| MedChemExpress | 50 mg | 2650.98 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.82% |
GSK461364 is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by 5-carbamoyl-4-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophen-2-yl and (4-methylpiperazin-1-yl)methyl groups at positions 1 and 6, respectively. It is an ATP-competitive polo-like kinase 1 (PLK1) inhibitor (Ki = 2.2 nM). It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a primary carboxamide, a member of benzimidazoles, an ether, a member of thiophenes, a N-methylpiperazine and a member of (trifluoromethyl)benzenes.
Source: ChEBI
| Molecular formula | C27H28F3N5O2S |
|---|---|
| Molecular weight | 543.6 g/mol |
| IUPAC name | 5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide |
| InChIKey | ZHJGWYRLJUCMRT-QGZVFWFLSA-N |
| SMILES | C[C@H](C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N |
Computed by PubChem (NCBI)