Products 1816331-66-4

CAS 1816331-66-4 appears in our catalog under these names: GSK864, 99%, GSK864/ 97.07% (existing batch purity), GSK864, GSK864 97%, (S)-1-(4-Fluorobenzyl)-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3,7-dicarboxamide, 97%, 97%. Offered by: AmBeed, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 100mg, 1mg, 5mg, 10mg, 25mg, 50mg, 2mg, 10mM/1mL.

GSK864, 99%
AmBeed
  • size: 100mg
  • Variants: 1
from 39676.84
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GSK864/ 97.07% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 624.84
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GSK864
GLPBio, Biosynth
  • size: 10mg, 5mg, 25mg, 50mg
  • Variants: 5
from 1107.21
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GSK864 97%
Ambeed
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 5
from 420.44
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(S)-1-(4-Fluorobenzyl)-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3,7-dicarboxamide, 97%, 97%
Chemat
  • size: 1mg, 50mg, 100mg, 5mg
  • Variants: 6
from 309.20
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GSK864, 99.91%
MedChemExpress
  • size: 10mM/1mL, 50 mg, 10 mg, 100 mg
  • Variants: 6
from 1030.22
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Structural formula: {0} (CAS {1})

GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor; inhibits IDH1 mutants R132C, R132H, and R132G with IC50 values of 8.8, 15.2 and 16.6 nM.

Source: ChEBI

Identity
Molecular formulaC30H31FN6O4
Molecular weight558.6 g/mol
IUPAC name(7S)-1-[(4-fluorophenyl)methyl]-3-N-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,6-dihydropyrazolo[4,5-c]pyridine-3,7-dicarboxamide
InChIKeyDUCNNEYLFOQFSW-PMERELPUSA-N
SMILESCC1=CC(=CC(=C1OC)C)NC(=O)C2=NN(C3=C2CN(C[C@]3(C)C(=O)N)C(=O)C4=CC=CN4)CC5=CC=C(C=C5)F

Computed by PubChem (NCBI)

Synonyms: compound 4 [PMID: 26436839], orb1707237