Glasdegib 98+%
cas: 1095173-27-5 — see every product listed under this CAS number, including other names
Glasdegib 98+% (CAS 1095173-27-5) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A575113-1mg |
| cas | 1095173-27-5 |
| size | 1mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 259.12 Pln | |
| Ambeed | 5mg | 492.75 Pln | |
| Ambeed | 10mg | 726.38 Pln | |
| Ambeed | 25mg | 1188.06 Pln | |
| Ambeed | 50mg | 1855.56 Pln | |
| Ambeed | 100mg | 2790.06 Pln | |
| Ambeed | 250mg | 4670.19 Pln |
properties
| purity | 98+% |
|---|---|
| delivery time | 1-2 weeks |
| ambeed catalog no. | A575113 |
Glasdegib is a member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a (2R,4S)-4-{[(4-cyanophenyl)carbamoyl]amino}-1-methylpiperidin-2-yl group at position 2. It is a hedgehog signalling pathway inhibitor that acts by binding to Smoothened (SMO) receptors and blocking signal transduction (IC50 = 5 nM). It is used in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients (aged 75 years), or who have medical conditions that prevent the use of standard chemotherapy. It has a role as a Hedgehog signaling pathway inhibitor, an antineoplastic agent and a SMO receptor antagonist. It is a member of phenylureas, a nitrile, a member of benzimidazoles and a member of piperidines.
Source: ChEBI
| Molecular formula | C21H22N6O |
|---|---|
| Molecular weight | 374.4 g/mol |
| IUPAC name | 1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea |
| InChIKey | SFNSLLSYNZWZQG-VQIMIIECSA-N |
| SMILES | CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N |
Computed by PubChem (NCBI)