Golgicide A

cas: 1139889-93-2 — see every product listed under this CAS number, including other names

Golgicide A (CAS 1139889-93-2) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1mg, 5mg, 10mg, 25mg. Offered by: TRC, Biosynth, GLPBio.

brandTRC
catalog numberTRC-G766500-100MG
cas1139889-93-2
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
Biosynth 1mg price on request
Biosynth 5mg price on request
Biosynth 10mg price on request
GLPBio 10mg 901.27 Pln
GLPBio 25mg 1369.32 Pln
GLPBio 5mg 690.65 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Golgicide A is a diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181). It has a role as a cis-Golgi ArfGEF GBF inhibitor. It contains a cis-golgicide A and a trans-golgicide A.

Source: ChEBI

Identity
Molecular formulaC17H14F2N2
Molecular weight284.30 g/mol
IUPAC name(3aR,9bS)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
InChIKeyNJZHEQOUHLZCOX-FTLRAWMYSA-N
SMILESC1C=C[C@H]2[C@@H]1C(NC3=C2C=C(C=C3F)F)C4=CN=CC=C4

Computed by PubChem (NCBI)

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